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Facts

Copper is involved in the absorption, storage and metabolism of iron.

   




The human body contains approximately 50 milligrams (mg) to 120 mg of copper. Copper concentrates in the brain, heart, kidney, but is highest in the liver where it contributes to energy and detoxification processes.1 Blood values typically average 120 mg/dl for women and 109 mg/dl for men.

   


Copper is absorbed primarily in the small intestine and to a certain extent, the stomach.

   





Increased consumption of fructose can significantly worsen a copper deficiency, according to researchers with the U.S. Department of Agriculture. Individuals who consumed 20 % of their daily calories from fructose showed decreased levels of red blood cell superoxide dismutase (SOD), a copper-dependent enzyme essential for antioxidant protection within the red blood cell.2

 
Functions


Aids in the formation of bone, haemoglobin, red blood cells.2 Copper aids in the conversion and transport of iron from the intestinal lumen into red blood cells.

   

Works in balance with zinc and vitamin C to form elastin.2

   


Involved in the healing process, energy production, hair and skin colouring and taste sensitivity.2

   
Involved in the development and maintenance of the cardiovascular system.
   


Helps maintain the myelin, the insulation that sheaths nerves and aids in the transmission signals from the brain to the body and vice versa.

   


Involved in producing and regulating neurotransmitters in the brain, including norepinephrine.

   



Plays a role in the activation of superoxide dismutase, an antioxidant enzyme that is a free radical scavenger. Copper also protects against oxidative damage especially in the thyroid, uterus, lungs, liver, brain, red blood cells, kidneys and pituitary.

 

Requirements

There is no current Recommended Daily Allowance set for Copper.

Signs of Deficiency
Signs of copper deficiency include: general weakness, osteoporosis, anaemia, baldness, diarrhoea, general weakness, skin sores and poor respiratory function. 2,4

Safety
Too much copper can cause an upset stomach and nausea. Copper absorption can be decreased by an excess intake of dietary iron or zinc. Vitamin C supplementation results in decreased copper.3

Signs of Toxicity
If consumed by a child, copper (3 grams) can be fatal. Occasional copper toxicity has been reported in individuals consuming drinking water that passes through copper water pipes where the copper has leached into the drinking water. Symptoms of copper toxicity include: nausea, anaemia, weakness, diarrhoea, headache, a metallic taste in the mouth,2 depigmentation, dermatitis and neurologic impairments. 1 Wilson's disease is a genetic disorder where there is an excessive accumulation of copper in the soft tissues that can result in damage to the kidneys, brain and liver.

Current Research

Osteoporosis
Copper is involved in cross linking of collagen in bone and therefore, has implications for osteoporosis. In postmenopausal women supplementation of copper and zinc has been association with conservation of bone density and preventing spinal bone loss. 5 Researchers at the University of Ulster in Ireland conclude that copper plays an important role in the prevention of osteoporosis. Seventy-three postmenopausal women supplemented their diets with either 3 milligrams of copper or a placebo. Two years later, when the study ended, the supplemented group maintained bone mineral density while the placebo group lost significant amounts of bone.6

Immune Function
A copper deficient diet can result in impaired immune function even after increased intakes of dietary copper return blood copper levels to normal.7 study, conducted at the U.S. Department of Agriculture's Western Human Nutrition Research Center in San Francisco found that healthy men fed a copper-poor diet for two months followed by diets containing 2 to 3 mg of copper (within the recommended range) showed that indices of immune function declined during the copper-deficient period and remained compromised even after the increased dietary intakes of copper had returned blood copper levels to normal.

Growth
Copper "...reduces growth rate through effects on both food intake and efficiency of food utilisation for growth," conclude researchers at the University of California at Davis.8 The study, using rats, found that a copper deficient diet stunted growth.

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1 Schauss, A. Minerals and human health: the rationale for optimal and balanced trace element levels. Life Sciences Press, 1995: pp.24-25.

2 Balch, J.F. and P.A. Prescription for Nutritional Healing. Avery Publishing, 1997.

3 Medeiros D., Percival S., Copper.
http://www.nutrition.org/nutinfo/content/copp.shtml.

4 Dunne, L.J. Nutrition Almanac, 3rd ed. McGraw-Hill Publishing Company, 1990:71-72.

5 Nielsen F., Davis C., Milne D. Low dietary zinc and copper negatively affect plasma and urine indicators of bonehealth. USDA, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, N.D.
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